Shoot one handed and see if it still hitting in same area. If not, it could be your support hand. A buddy had this same issue (7-9 O'clock) with a 1911. He realized it was his support grip (thumb) throwing him low-left.With my P320 compact my shot pattern is consistently in the 7-9 o'clock position. In a steady rest it is fine. I have worked on my trigger pull, but haven't noticed an improvement. I have fairly large hands. Would increasing the frame from a medium to large make any difference or am I overthinking this?
Shoot strong-hand and slowly introduce the support adding more and tighter grip each time to find the "proper" grip for you and that pistol.